[35] Florianopolis 7-6,6-7,6-4 Christopher O'Connell [132] 2021-06-27 16:00
Stadium: Stadium Court Round: 27 Ground: Hardcourt outdoor
Home History
| French Open | 2021/06/04 19:00 | Stefanos Tsitsipas v John Isner | 5-7,6-3,7-6,6-1 |
| French Open | 2021/06/02 12:35 | Filip Krajinovic v John Isner | 6-7,1-6,6-7 |
| French Open | 2021/05/31 09:00 | Sam Querrey v John Isner | 6-7,3-6,4-6 |
| ATP Madrid | 2021/05/07 11:00 | Dominic Thiem v John Isner | 3-6,6-3,6-4 |
| ATP Madrid | 2021/05/06 13:20 | John Isner v Andrey Rublev | 7-6,3-6,7-6 |
| ATP Madrid | 2021/05/05 16:00 | Roberto Bautista-Agut v John Isner | 4-6,7-6,6-7 |
| ATP Madrid | 2021/05/03 09:00 | John Isner v Miomir Kecmanovic | 6-4,7-6 |
| ATP Miami | 2021/03/30 15:00 | John Isner v Roberto Bautista-Agut | 3-6,6-4,6-7 |
Away History
| Wimbledon | 2021/06/24 12:00 | Christopher O'Connell v Tomas Machac | 7-6,6-4,7-6 |
| Wimbledon | 2021/06/23 13:25 | Christopher O'Connell v Ruben Bemelmans | 6-7,6-3,7-5 |
| Wimbledon | 2021/06/22 10:00 | Christopher O'Connell v Filip Horansky | 3-6,6-1,9-7 |
| ATP Halle | 2021/06/13 12:50 | Christopher O'Connell v Arthur Rinderknech | 6-3,4-6,2-6 |
| ATP Halle | 2021/06/12 12:50 | Radu Albot v Christopher O'Connell | 6-4,3-6,5-7 |
| French Open | 2021/05/31 11:30 | Tommy Paul v Christopher O'Connell | 6-2,6-4,4-6,4-6,10-8 |
| ATP Belgrade | 2021/05/24 15:50 | Christopher O'Connell v Andrej Martin | 6-3,6-7,5-7 |
| ATP Belgrade | 2021/05/23 10:25 | Christopher O'Connell v Lukas Klein | 7-6,7-5 |