Stadium: G.B. Hodge Center
Home Manager: Dave Dickerson Away Manager: Barclay Radebaugh
| NCAAB | 2020/02/10 23:00 | Charleston Southern v USC Upstate | L | 52-66 |
| NCAAB | 2020/01/03 00:30 | USC Upstate v Charleston Southern | W | 75-89 |
| NCAAB | 2019/03/06 00:00 | USC Upstate v Charleston Southern | W | 52-71 |
| NCAAB | 2019/02/22 00:30 | USC Upstate v Charleston Southern | W | 60-92 |
| NCAAB | 2019/02/02 21:30 | Charleston Southern v USC Upstate | W | 90-71 |
| NCAAB | 2017/11/18 19:00 | USC Upstate v Charleston Southern | W | 72-82 |
| NCAAB | 2016/11/19 22:30 | Charleston Southern v USC Upstate | L | 77-79 |
| NCAAB | 2021/11/23 00:00 | Charleston Southern v Georgia Tech | L | 70-85 |
| NCAAB | 2021/11/20 20:00 | Charleston Southern v Bob Jones University | W | 119-63 |
| NCAAB | 2021/11/18 00:00 | Charleston Southern v Wake Forest | L | 59-95 |
| NCAAB | 2021/11/13 00:00 | Charleston Southern v Mississippi | L | 68-93 |
| NCAAB | 2021/11/10 00:00 | Charleston Southern v Johnson & Wales (NC) | W | 118-71 |
| NCAAB | 2021/02/22 23:00 | Charleston Southern v Presbyterian | W | 78-77 |
| NCAAB | 2021/02/19 23:00 | Longwood v Charleston Southern | L | 64-58 |
| NCAAB | 2021/02/19 00:00 | Longwood v Charleston Southern | L | 70-62 |
| NCAAB | 2021/11/19 00:00 | USC Upstate v East Tenn St | L | 43-56 |
| NCAAB | 2021/11/15 23:00 | USC Upstate v St. Andrew's | W | 96-43 |
| NCAAB | 2021/11/13 00:00 | USC Upstate v Charlotte U | L | 64-76 |
| NCAAB | 2021/11/10 00:00 | USC Upstate v SC Gamecocks | L | 60-78 |
| NCAAB | 2021/02/27 21:00 | USC Upstate v High Point | L | 60-65 |
| NCAAB | 2021/02/22 23:00 | Gardner Webb v USC Upstate | L | 69-58 |
| NCAAB | 2021/02/18 22:00 | USC Upstate v Presbyterian | W | 65-51 |
| NCAAB | 2021/02/15 23:00 | USC Upstate v Presbyterian | L | 65-75 |