[6] TEN Titans 5-2 NJ Devils [14] 2021-12-04 05:00
Stadium: Prudential Center
Home Manager: Don Granato Away Manager: Lindy Ruff
Head to Head
| NHL | 2021/10/23 23:00 | BUF Sabres v NJ Devils | L | 1-2 |
| NHL | 2021/04/08 23:00 | NJ Devils v BUF Sabres | L | 6-3 |
| NHL | 2021/04/06 23:00 | BUF Sabres v NJ Devils | W | 5-3 |
| NHL | 2021/03/16 23:00 | BUF Sabres v NJ Devils | L | 2-3 |
| NHL | 2021/02/26 00:00 | NJ Devils v BUF Sabres | L | 4-3 |
| NHL | 2021/02/24 00:00 | BUF Sabres v NJ Devils | W | 4-1 |
| NHL | 2021/02/20 17:30 | BUF Sabres v NJ Devils | W | 3-2 |
| NHL | 2021/01/31 18:00 | NJ Devils v BUF Sabres | L | 5-3 |
Home History
| NHL | 2021/12/03 00:00 | BUF Sabres v FLA Panthers | L | 4-7 |
| NHL | 2021/11/30 00:00 | SEA Kraken v BUF Sabres | L | 7-4 |
| NHL | 2021/11/28 00:00 | BUF Sabres v DET Red Wings | L | 2-3 |
| NHL | 2021/11/27 00:00 | MTL Canadiens v BUF Sabres | W | 1-4 |
| NHL | 2021/11/25 00:00 | BOS Bruins v BUF Sabres | L | 5-1 |
| NHL | 2021/11/23 00:00 | CLB Blue Jackets v BUF Sabres | L | 7-4 |
| NHL | 2021/11/21 23:00 | BUF Sabres v NY Rangers | L | 4-5 |
| NHL | 2021/11/19 00:00 | CGY Flames v BUF Sabres | L | 5-0 |
Away History
| NHL | 2021/12/04 01:00 | NJ Devils v WPG Jets | L | 4-8 |
| NHL | 2021/12/03 01:00 | NJ Devils v MIN Wild | L | 2-5 |
| NHL | 2021/12/01 00:00 | SJ Sharks v NJ Devils | L | 5-2 |
| NHL | 2021/11/29 00:00 | PHI Flyers v NJ Devils | W | 2-5 |
| NHL | 2021/11/26 23:00 | NJ Devils v NSH Predators | L | 2-4 |
| NHL | 2021/11/25 00:30 | MIN Wild v NJ Devils | L | 3-2 |
| NHL | 2021/11/20 21:00 | NJ Devils v TB Lightning | W | 5-3 |
| NHL | 2021/11/19 00:00 | NJ Devils v FLA Panthers | L | 1-4 |