[9] Harlequins 50-21 Northampton [10] 2017-11-17 08:00
Stadium: London Round: 12
Referee: JP Doyle Home Manager: Mark Mapletoft Away Manager: Alan Dickens
Head to Head
| Premiership Rugby | 2017/09/30 14:00 | Northampton v Harlequins | L | 30-22 |
| Premiership Rugby | 2017/05/06 15:00 | Northampton v Harlequins | L | 22-20 |
| Premiership Rugby | 2016/10/08 14:00 | Harlequins v Northampton | W | 20-9 |
| Premiership Rugby | 2016/03/27 14:15 | Northampton v Harlequins | L | 29-23 |
| Premiership Rugby | 2016/02/06 14:00 | Harlequins v Northampton | L | 23-27 |
| Premiership Rugby | 2015/02/27 19:45 | Northampton v Harlequins | L | 17-13 |
| Premiership Rugby | 2014/12/27 16:30 | Harlequins v Northampton | L | 25-30 |
| European Rugby Challenge Cup | 2014/04/25 19:00 | Northampton v Harlequins | L | 18-10 |
Home History
| LV Cup | 2017/11/12 15:00 | Harlequins v Worcester Warriors | W | 45-37 |
| LV Cup | 2017/11/05 15:00 | Saracens v Harlequins | W | 29-30 |
| Premiership Rugby Shield | 2017/10/29 14:15 | Harlequins v Saracens Storm | W | 40-26 |
| Premiership Rugby | 2017/10/28 14:00 | Harlequins v Worcester Warriors | W | 41-35 |
| Premiership Rugby Shield | 2017/10/23 18:30 | Gloucester United v Harlequins | W | 26-36 |
| European Rugby Champions Cup | 2017/10/22 16:30 | Wasps v Harlequins | L | 41-10 |
| European Rugby Champions Cup | 2017/10/14 16:30 | Harlequins v La Rochelle | L | 27-34 |
| Premiership Rugby | 2017/10/06 18:45 | Harlequins v Sale Sharks | W | 42-26 |
Away History
| LV Cup | 2017/11/11 17:15 | Northampton v Newport Gwent Dragons | W | 41-7 |
| LV Cup | 2017/11/04 15:00 | Exeter Chiefs v Northampton | L | 43-28 |
| Premiership Rugby | 2017/10/28 14:00 | Northampton v Wasps | L | 22-38 |
| European Rugby Champions Cup | 2017/10/21 14:15 | Clermont v Northampton | L | 24-7 |
| European Rugby Champions Cup | 2017/10/15 16:30 | Northampton v Saracens | L | 13-57 |
| Premiership Rugby | 2017/10/07 14:00 | Gloucester v Northampton | L | 29-24 |
| Premiership Rugby | 2017/09/30 14:00 | Northampton v Harlequins | W | 30-22 |
| Premiership Rugby | 2017/09/24 14:00 | London Irish v Northampton | W | 25-40 |