Head to Head
| NHL Pre-Season | 2021/10/07 00:00 | STL Blues v MIN Wild | W | 3-4 |
| NHL Pre-Season | 2021/09/26 00:00 | MIN Wild v STL Blues | L | 2-6 |
| NHL | 2021/05/14 00:00 | MIN Wild v STL Blues | L | 3-7 |
| NHL | 2021/05/13 01:00 | MIN Wild v STL Blues | L | 0-4 |
| NHL | 2021/05/02 00:00 | STL Blues v MIN Wild | W | 3-4 |
| NHL | 2021/04/30 00:00 | STL Blues v MIN Wild | L | 5-4 |
| NHL | 2021/04/28 23:00 | STL Blues v MIN Wild | L | 4-3 |
| NHL | 2021/04/11 00:00 | MIN Wild v STL Blues | L | 2-3 |
Home History
| NHL | 2021/12/05 00:00 | TOR Maple Leafs v MIN Wild | W | 3-4 |
| NHL | 2021/12/03 01:00 | NJ Devils v MIN Wild | W | 2-5 |
| NHL | 2021/12/01 01:00 | ARZ Coyotes v MIN Wild | W | 2-5 |
| NHL | 2021/11/28 19:00 | TB Lightning v MIN Wild | W | 2-4 |
| NHL | 2021/11/26 20:30 | WIN Jets v MIN Wild | W | 1-7 |
| NHL | 2021/11/25 00:30 | MIN Wild v NJ Devils | W | 3-2 |
| NHL | 2021/11/21 22:00 | MIN Wild v TB Lightning | L | 4-5 |
| NHL | 2021/11/20 23:00 | MIN Wild v FLA Panthers | L | 4-5 |
Away History
| NHL | 2021/12/04 18:00 | STL Blues v FLA Panthers | L | 3-4 |
| NHL | 2021/12/03 00:00 | STL Blues v TB Lightning | L | 2-4 |
| NHL | 2021/12/01 01:00 | TB Lightning v STL Blues | W | 3-4 |
| NHL | 2021/11/28 01:00 | CLB Blue Jackets v STL Blues | W | 3-6 |
| NHL | 2021/11/26 20:30 | STL Blues v CHI Blackhawks | L | 2-3 |
| NHL | 2021/11/25 00:30 | STL Blues v DET Red Wings | L | 2-4 |
| NHL | 2021/11/23 01:00 | VGS Golden Knights v STL Blues | W | 2-5 |
| NHL | 2021/11/21 01:00 | STL Blues v DAL Stars | L | 1-4 |