Head to Head
| NHL Pre-Season | 2021/10/07 00:00 | STL Blues v MIN Wild | W | 3-4 |
| NHL Pre-Season | 2021/09/26 00:00 | MIN Wild v STL Blues | L | 2-6 |
| NHL | 2021/05/14 00:00 | MIN Wild v STL Blues | L | 3-7 |
| NHL | 2021/05/13 01:00 | MIN Wild v STL Blues | L | 0-4 |
| NHL | 2021/05/02 00:00 | STL Blues v MIN Wild | W | 3-4 |
| NHL | 2021/04/30 00:00 | STL Blues v MIN Wild | L | 5-4 |
| NHL | 2021/04/28 23:00 | STL Blues v MIN Wild | L | 4-3 |
| NHL | 2021/04/11 00:00 | MIN Wild v STL Blues | L | 2-3 |
Home History
| NHL | 2021/12/13 02:00 | MIN Wild v VGS Golden Knights | L | 4-6 |
| NHL | 2021/12/12 03:30 | MIN Wild v LA Kings | L | 1-2 |
| NHL | 2021/12/10 03:30 | MIN Wild v SJ Sharks | W | 5-2 |
| NHL | 2021/12/08 02:00 | MIN Wild v EDM Oilers | W | 4-1 |
| NHL | 2021/12/05 00:00 | TOR Maple Leafs v MIN Wild | W | 3-4 |
| NHL | 2021/12/03 01:00 | NJ Devils v MIN Wild | W | 2-5 |
| NHL | 2021/12/01 01:00 | ARZ Coyotes v MIN Wild | W | 2-5 |
| NHL | 2021/11/28 19:00 | TB Lightning v MIN Wild | W | 2-4 |
Away History
| NHL | 2021/12/13 00:00 | ANA Ducks v STL Blues | L | 3-2 |
| NHL | 2021/12/12 00:00 | MON Canadiens v STL Blues | W | 1-4 |
| NHL | 2021/12/10 01:00 | DET Red Wings v STL Blues | W | 2-6 |
| NHL | 2021/12/08 01:00 | FLA Panthers v STL Blues | W | 3-4 |
| NHL | 2021/12/04 18:00 | STL Blues v FLA Panthers | L | 3-4 |
| NHL | 2021/12/03 00:00 | STL Blues v TB Lightning | L | 2-4 |
| NHL | 2021/12/01 01:00 | TB Lightning v STL Blues | W | 3-4 |
| NHL | 2021/11/28 01:00 | CLB Blue Jackets v STL Blues | W | 3-6 |