[10] John Isner 4-6,4-6,4-6 Juan Martin Del Potro [6] 2018-01-06 20:40
Stadium: Court Suzanne Lenglen Round: 26 Ground: Clay
Head to Head
| ATP Paris | 2017/11/03 13:00 | Juan Martin Del Potro v John Isner | 4-6,7-6,4-6 |
| ATP Montreal | 2017/08/07 22:30 | Juan Martin Del Potro v John Isner | 7-5,7-5 |
| ATP Stockholm | 2016/10/19 16:30 | John Isner v Juan Martin Del Potro | 4-6,6-7 |
Home History
| ATP Paris | 2017/11/04 13:00 | Filip Krajinovic v John Isner | 6-4,6-7,7-6 |
| ATP Paris | 2017/11/03 13:00 | Juan Martin Del Potro v John Isner | 4-6,7-6,4-6 |
| ATP Paris | 2017/11/02 13:40 | John Isner v Grigor Dimitrov | 7-6,5-7,7-6 |
| ATP Paris | 2017/11/01 10:00 | John Isner v Diego Schwartzman | 7-6,6-7,6-3 |
| ATP Vienna | 2017/10/23 15:00 | Philipp Kohlschreiber v John Isner | 7-6,6-4 |
| ATP Shanghai | 2017/10/12 13:25 | Viktor Troicki v John Isner | 6-4,7-6 |
| ATP Shanghai | 2017/10/11 12:20 | Stefanos Tsitsipas v John Isner | 6-7,6-7 |
| ATP Shanghai | 2017/10/10 05:00 | Dusan Lajovic v John Isner | 6-4,6-7,6-7 |
Away History
| ATP Paris | 2017/11/03 13:00 | Juan Martin Del Potro v John Isner | 4-6,7-6,4-6 |
| ATP Paris | 2017/11/02 10:00 | Robin Haase v Juan Martin Del Potro | 5-7,4-6 |
| ATP Paris | 2017/11/01 15:45 | Joao Sousa v Juan Martin Del Potro | 2-6,2-6 |
| ATP Basel | 2017/10/29 14:00 | Roger Federer v Juan Martin Del Potro | 6-7,6-4,6-3 |
| ATP Basel | 2017/10/28 12:30 | Juan Martin Del Potro v Marin Cilic | 6-4,6-4 |
| ATP Basel | 2017/10/27 13:00 | Roberto Bautista-Agut v Juan Martin Del Potro | 2-6,6-2,4-6 |
| ATP Basel | 2017/10/26 13:00 | Julien Benneteau v Juan Martin Del Potro | 4-6,4-6 |
| ATP Basel | 2017/10/25 18:00 | Joao Sousa v Juan Martin Del Potro | 1-6,6-4,1-6 |